The Science Behind Polynucleotides:
Rejuvenation from Within
By FACE
Figure 1: Skin Elasticity Assessment
I t is often said that true beauty radiates from within. In the realm of modern aesthetic medicine, this sentiment has never been more scientifically accurate. We are witnessing a massive paradigm shift—moving away from merely "filling" lines and towards actually repairing the biological fabric of the skin itself.
Key Takeaways
- 01. Polynucleotides are not fillers; they are bio-stimulators derived from salmon DNA.
- 02. They trigger your cells to produce their own collagen and elastin.
- 03. Best for under-eye hollows, crepey neck skin, and acne scarring.
The Mechanism of Action
For years, hyaluronic acid fillers have reigned supreme as the gold standard for volume restoration. While they remain invaluable for structural contouring, they do not inherently change the behavior of your skin cells. They are the architects, but not the builders.
Polynucleotides function differently. Once injected, they act as "scavengers" against free radicals and signal your fibroblasts (the cells responsible for skin structure) to multiply. This leads to a thickening of the epidermis and a genuine improvement in skin quality over 90 days.
"We are not just masking the signs of aging; we are instructing the skin to behave younger."
Fillers vs. Polynucleotides
The most common question I receive in our Knightsbridge clinic is: "Do I need filler or Polynucleotides?" The answer depends on your goal. If you need immediate lift and shape (e.g., cheekbones), fillers are superior. If you need to fix texture, dark circles, or thin, crepey skin, Polynucleotides are the gold standard.
Book Your ConsultationExpected Results & Downtime
This is a "slow burn" treatment. You will typically require 3 sessions, spaced 3 weeks apart. The magic happens in the weeks following the second treatment. Downtime is minimal—usually small bumps at the injection site that disappear within 12-24 hours.